This grant is in support of the overall eye research activities of the Research Division of the Department of Ophthalmology. It provides the investigators with telephone, secretarial, laundry, photographic and histological services. Furthermore, it pays for the maintenance of the instruments used by the majority of the research grants. The centralization of the above-mentioned services provides an efficient operation with a considerable saving of funds. The Research Division is organized into seven laboratories under the direction of the senior staff: Matrix Biology-Head, E.A. Balazs; Immunology-Head, W. Manski; Developmental Biology-Head, J.G. Hollyfield; Biochemistry and Molecular Biology-Head, A. Spector; Pharmacology-Head, K. Eakins; Membrane Biology-Head, J. Fischbarg; and Physiology-Head, L.Z. Bito. These laboratories house the activities of 26 full-time research scientists with Ph.D. or M.D. degrees, 39 technical personnel and 6 research secretaries. The services under this grant benefit 25 NIH research grants operating entirely in the Research Division.